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8-Azanebularine

8-Azanebularine is a potent inhibitor of human ADAR2, exhibiting high-affinity binding (KD=2 nM) when incorporated into RNA and effectively blocking the editing reaction (IC50=15 mM) . This makes it a valuable chemical tool for studying ADAR-mediated RNA editing mechanisms in both in vitro and cellular research applications.

Product Specifications

CAS Number

38874-46-3

Field of Research

Metabolism Research

Smiles

O[C@H]1[C@H] (N2C=3C (N=N2) =CN=CN3) O[C@H] (CO) [C@H]1O

Molecular Formula

C9H11N5O4

Molecular Weight

253.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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