8-Azanebularine
8-Azanebularine is a potent inhibitor of human ADAR2, exhibiting high-affinity binding (KD=2 nM) when incorporated into RNA and effectively blocking the editing reaction (IC50=15 mM) . This makes it a valuable chemical tool for studying ADAR-mediated RNA editing mechanisms in both in vitro and cellular research applications.
Product Specifications
CAS Number
38874-46-3
Field of Research
Metabolism Research
Smiles
O[C@H]1[C@H] (N2C=3C (N=N2) =CN=CN3) O[C@H] (CO) [C@H]1O
Molecular Formula
C9H11N5O4
Molecular Weight
253.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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