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P53 Activator 5

P53 Activator 5 is a potent small molecule that reactivates mutant p53 by restoring its DNA-binding function, with a SC150 value below 0.05 mM. It has demonstrated significant anti-tumor activity in both cellular assays and in vivo models, supporting its use in oncology research targeting p53-mutant cancers.

Product Specifications

CAS Number

2636840-37-2

Field of Research

Cancer Biology, Cell Biology

Smiles

N (C1=C2C (N (CC (F) (F) F) C (C#CCNC3=C (OC) C=C (C (F) (F) F) C=C3) =C2) =CC=C1) [C@@H]4CC[C@@H] (N (C) C) CC4

Molecular Formula

C29H32F6N4O

Molecular Weight

566.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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