P53 Activator 7
P53 Activator 7 is a potent, cell-permeable small molecule that selectively stabilizes and reactivates the p53 Y220C mutant protein, triggering apoptotic cell death. Its application in cancer research includes in vitro studies in mutant p53 cell lines and in vivo proof-of-concept models investigating tumor suppression.
Product Specifications
CAS Number
2849340-59-4
Product Name Alternative
Apoptosis, MDM-2/p53
Field of Research
Cancer Biology, Cell Biology
Purity
98.16% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.39 mM) ; DMSO:80 mg/mL (154.88 mM)
Smiles
O=P (C1=CC=C (C=C1) NCC#CC2=CC=3C (=CC=CC3N2CC (F) (F) F) NC4CCN (C) CC4) (C) C
Molecular Formula
C27H32F3N4OP
Molecular Weight
516.538
Storage Conditions
-20°C
Notes
For research use only.
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