Junceellolide C

Junceellolide C is a potent small molecule inhibitor of hepatitis B virus (HBV) replication. It functions by targeting the covalently closed circular DNA (cccDNA) transcription, effectively suppressing both HBV DNA and RNA production in cellular models like HepAD38 cells, with EC50 values in the low micromolar range. This mechanism supports its investigation as a promising candidate for antiviral research targeting chronic HBV infection.

Product Specifications

CAS Number

121769-82-2

Field of Research

Infectious Disease & Virology

Smiles

C[C@@]12[C@] ([C@@]3 (CO3) CC[C@@H]1OC (C) =O) ([C@H] (OC (C) =O) [C@@]4 (O) [C@@] (OC (=O) [C@@H]4C) ([C@@H] (Cl) C (=C) /C=C\[C@@H]2OC (C) =O) [H]) [H]