E7766 disodium
E7766 disodium is a potent, macrocycle-bridged STING agonist with a 40 nM binding affinity (Kd) . It demonstrates broad pan-genotypic activity and robust antitumor effects, supporting its investigation in cancer immunotherapy research across both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2242636-28-6
Field of Research
Immunology & Inflammation
Smiles
O=[P@@] (OC[C@@H]1[C@@H] (O2) [C@@H] (F) [C@H] ([N@@]3C=NC (C3=NC=N4) =C4NC/C=C/CN5) O1) (O[C@H] ([C@H]6CO[P@@]2 ([S-]) =O) [C@@H] (F) [C@@H] (O6) [N@]7C8=NC=NC5=C8N=C7) [S-].[Na+].[Na+]
Molecular Formula
C24H26F2N10Na2O8P2S2
Molecular Weight
792.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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