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E7766 disodium

E7766 disodium is a potent, macrocycle-bridged STING agonist with a 40 nM binding affinity (Kd) . It demonstrates broad pan-genotypic activity and robust antitumor effects, supporting its investigation in cancer immunotherapy research across both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2242636-28-6

Field of Research

Immunology & Inflammation

Smiles

O=[P@@] (OC[C@@H]1[C@@H] (O2) [C@@H] (F) [C@H] ([N@@]3C=NC (C3=NC=N4) =C4NC/C=C/CN5) O1) (O[C@H] ([C@H]6CO[P@@]2 ([S-]) =O) [C@@H] (F) [C@@H] (O6) [N@]7C8=NC=NC5=C8N=C7) [S-].[Na+].[Na+]

Molecular Formula

C24H26F2N10Na2O8P2S2

Molecular Weight

792.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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