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MDM2-p53-IN-16

MDM2-p53-IN-16 is a highly potent small molecule inhibitor of the MDM2-p53 interaction with an IC50 of 4.3 nM. It reactivates p53 function, inducing apoptosis and cell-cycle arrest in Glioblastoma Multiforme (GBM) cells in vitro, making it a valuable chemical probe for oncology research and p53 pathway studies.

Product Specifications

CAS Number

1917350-09-4

Field of Research

Cancer Biology; Cell Biology, Cell Biology

Smiles

C (C (N[C@@H] (CC1=CC=CC=C1) C (N[C@H] (C (OC) =O) CC (C) C) =O) =O) (=O) C2=C (NC=3C2=CC=CC3) C4=CC=CC=C4

Molecular Formula

C32H33N3O5

Molecular Weight

539.62

Storage Conditions

-20°C

Notes

For research use only.

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