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SHP2/HDAC-IN-1

SHP2/HDAC-IN-1 is a potent dual allosteric inhibitor of SHP2 (IC50=20.4 nM) and HDAC1 (IC50=25.3 nM) . It demonstrates potential for cancer immunotherapy research by activating T-cells, enhancing antigen presentation, and promoting cytokine secretion in preclinical studies.

Product Specifications

CAS Number

2831230-38-5

Field of Research

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Smiles

ClC1=C (C=CC=C1Cl) C=2C (N) =NC (=CN2) N3CCC (NCC4=CC=C (C (NCC5=CC=C (/C=C/C (NO) =O) C=C5) =O) C=C4) (C) CC3

Molecular Formula

C34H35Cl2N7O3

Molecular Weight

660.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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