SHP2/HDAC-IN-1
SHP2/HDAC-IN-1 is a potent dual allosteric inhibitor of SHP2 (IC50=20.4 nM) and HDAC1 (IC50=25.3 nM) . It demonstrates potential for cancer immunotherapy research by activating T-cells, enhancing antigen presentation, and promoting cytokine secretion in preclinical studies.
Product Specifications
CAS Number
2831230-38-5
Field of Research
Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Smiles
ClC1=C (C=CC=C1Cl) C=2C (N) =NC (=CN2) N3CCC (NCC4=CC=C (C (NCC5=CC=C (/C=C/C (NO) =O) C=C5) =O) C=C4) (C) CC3
Molecular Formula
C34H35Cl2N7O3
Molecular Weight
660.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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