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PARP-2/1-IN-2

PARP-2/1-IN-2 is the enantiomer of Veliparib and a potent PARP inhibitor with Kis of 2 nM (PARP-2) and 5 nM (PARP-1) . It demonstrates an EC50 of 3 nM in cellular PARP assays, making it a valuable chemical probe for studying DNA repair mechanisms in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

912444-01-0

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

C (N) (=O) C1=C2C (N=C (N2) [C@]3 (C) CCCN3) =CC=C1

Molecular Formula

C13H16N4O

Molecular Weight

244.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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