PKCiota-IN-1
PKCiota-IN-1 is a highly potent and selective small molecule inhibitor of protein kinase C iota (PKCι), with an IC50 of 2.7 nM. It also inhibits PKC-α and PKC-ε at higher concentrations. This compound is a valuable chemical probe for studying PKCι signaling in cancer cell proliferation and transformation in both cellular and animal models.
Product Specifications
CAS Number
2230052-97-6
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O (C) C1=C (C2=C3N (N=C2) C=CC (=C3) C4=C5C (=NC=C4) NC=C5) C=C6C (=C1) CC (CF) NC6
Molecular Formula
C25H22FN5O
Molecular Weight
427.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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