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VEGFR-3-IN-1

VEGFR-3-IN-1 is a potent and selective VEGFR3 inhibitor (IC50 = 110.4 nM) that blocks the VEGFR3 signaling pathway. It demonstrates antitumor activity by suppressing the proliferation and migration of VEGF-C-stimulated HDLECs and breast cancer cells like MDA-MB-231 in vitro.

Product Specifications

CAS Number

2756668-73-0

Product Name Alternative

VEGFR3

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.52% (May vary between batches)

Solubility

DMSO:1 mg/mL (1.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.62 mM)

Smiles

C (NC1=CC (C (F) (F) F) =C (Cl) C=C1) (=O) N2CCN (C3=C4C (SC (=C4) C5=CC=C (C=C5) N6CCN (C) CC6) =NC=N3) CC2

Molecular Formula

C29H29ClF3N7OS

Molecular Weight

616.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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