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CDK4/6-IN-15

CDK4/6-IN-15 is an orally bioavailable, selective CDK4/6 inhibitor that induces G1 cell cycle arrest. It functions by inhibiting Rb phosphorylation at S780 and downregulating E2F-driven gene expression, making it a valuable tool for studying cell cycle dynamics in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

2078047-99-9

Field of Research

Cell Biology, Signal Transduction

Smiles

CC1=C (SC (NC) =N1) C2=NC (NC3=CC=C (C=N3) N4CCC (N (C) C) CC4) =NC=C2F

Molecular Formula

C21H27FN8S

Molecular Weight

442.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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