CDK4/6-IN-15
CDK4/6-IN-15 is an orally bioavailable, selective CDK4/6 inhibitor that induces G1 cell cycle arrest. It functions by inhibiting Rb phosphorylation at S780 and downregulating E2F-driven gene expression, making it a valuable tool for studying cell cycle dynamics in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
2078047-99-9
Field of Research
Cell Biology, Signal Transduction
Smiles
CC1=C (SC (NC) =N1) C2=NC (NC3=CC=C (C=N3) N4CCC (N (C) C) CC4) =NC=C2F
Molecular Formula
C21H27FN8S
Molecular Weight
442.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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