TRK/ALK-IN-1
TRK/ALK-IN-1 is a potent, dual-specificity inhibitor targeting TRKA (IC50=2.2 nM) and both wild-type and L1196M-mutant ALK. Its strong correlation between enzymatic and cellular anti-proliferative activity makes it a valuable chemical probe for oncology research, supporting investigations into TRK and ALK-driven cancers in vitro.
Product Specifications
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CN1CCN (CC1) C2=C (C=C (C=C2) NC (=O) [C@@H]3CCCN3C4=NC (=NC=C4Cl) NC5=CC (=CC (=C5) F) F) C (=O) N6CCSCC6
Molecular Formula
C31H35ClF2N8O2S
Molecular Weight
657.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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