EIF4A3-IN-17
EIF4A3-IN-17 is a potent silvestrol analog that inhibits translation by disrupting eIF4F complex assembly, with EC50 values in the low nanomolar range. This compound is a valuable chemical probe for studying oncogenic protein synthesis and cancer biology in cellular models.
Product Specifications
CAS Number
1402931-75-2
Field of Research
Cell Biology
Smiles
O[C@]12[C@] ([C@@H] ([C@@H] (C (OC) =O) [C@H]1O) C3=CC=CC=C3) (OC=4C2=C (OC) C=C (C#N) C4) C5=CC=C (OC) C=C5
Molecular Formula
C28H25NO7
Molecular Weight
487.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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