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EIF4A3-IN-17

EIF4A3-IN-17 is a potent silvestrol analog that inhibits translation by disrupting eIF4F complex assembly, with EC50 values in the low nanomolar range. This compound is a valuable chemical probe for studying oncogenic protein synthesis and cancer biology in cellular models.

Product Specifications

CAS Number

1402931-75-2

Field of Research

Cell Biology

Smiles

O[C@]12[C@] ([C@@H] ([C@@H] (C (OC) =O) [C@H]1O) C3=CC=CC=C3) (OC=4C2=C (OC) C=C (C#N) C4) C5=CC=C (OC) C=C5

Molecular Formula

C28H25NO7

Molecular Weight

487.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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