Falcarindiol
Falcarindiol is an orally bioavailable polyacetylene that suppresses inflammation and cell proliferation. It inhibits LPS-induced NO production in macrophages by targeting the JAK/STAT pathway, reducing JAK1/JAK2 phosphorylation and STAT1 nuclear translocation to downregulate iNOS expression. This mechanism supports its research in inflammatory and cancer studies using both in vitro and in vivo models.
Product Specifications
CAS Number
55297-87-5
Product Name Alternative
Falcarindiol
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.38% (May vary between batches)
Solubility
DMSO:≥ 25 mg/mL
Smiles
C ([C@H] (/C=C\CCCCCCC) O) #CC#C[C@H] (C=C) O
Molecular Formula
C17H24O2
Molecular Weight
260.37
Storage Conditions
-20°C
Notes
For research use only.
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