(S) -JDQ-443
JDQ-443 is a selective, covalent, and orally bioavailable inhibitor targeting the KRAS G12C mutation. Its (S) -isomer form exhibits potent antitumor activity, as demonstrated in both cellular assays and in vivo preclinical models for oncology research.
Product Specifications
CAS Number
2653994-10-4
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC1=C (C (=NN1C2CC3 (C2) CN (C (C=C) =O) C3) C=4C=C5C (=CC4) N (C) N=C5) C6=C7C (=CC (C) =C6Cl) NN=C7
Molecular Formula
C29H28ClN7O
Molecular Weight
526.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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