(Rac) -SHIN2
(Rac) -SHIN2 is a potent and selective serine hydroxymethyltransferase (SHMT) inhibitor. It promotes NOTCH1-driven survival in primary T-ALL mouse models, making it a valuable chemical probe for studying T-cell acute lymphoblastic leukemia in both in vivo and in vitro experimental systems.
Product Specifications
CAS Number
2204289-53-0
Product Name Alternative
SHMT2
Field of Research
Infectious Disease & Virology, Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:80 mg/mL (196.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.12 mM)
Smiles
N#CC1=C (OC=2NN=C (C2C1 (C=3C=C (C#CCCCO) C=C (C3) CO) C (C) C) C) N
Molecular Formula
C23H26N4O3
Molecular Weight
406.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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