EIF4A3-IN-9
EIF4A3-IN-9 is a silvestrol analog that inhibits translation by disrupting eIF4F complex assembly, with EC50 values of 29, 450, and 80 nM against myc-LUC, tub-LUC, and MDA-MB-231 cell growth, respectively. It is a valuable chemical probe for studying oncogenic translation and cancer pathogenesis in cellular models.
Product Specifications
CAS Number
1402931-71-8
Field of Research
Cell Biology
Smiles
O[C@]12[C@] ([C@@H] ([C@@H] (C (OC) =O) [C@H]1O) C3=CC=CC=C3) (OC=4C2=C (OC) C=C (C (N) =O) C4) C5=CC=C (OC) C=C5
Molecular Formula
C28H27NO8
Molecular Weight
505.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
