KIF18A-IN-7
KIF18A-IN-7 is a potent, orally bioavailable small molecule inhibitor of the mitotic kinesin KIF18A, exhibiting an IC50 of 9.4 nM against its ATPase activity. This compound is a valuable chemical probe for investigating KIF18A's role in chromosome segregation and for exploring potential anticancer strategies in cellular and in vivo cancer models.
Product Specifications
CAS Number
2914878-00-3
Field of Research
Signal Transduction
Smiles
C (=O) (N1CC2 (C=3C1=CC=C (NS (C) (=O) =O) C3) CCC4 (CC2) CC4) C5=CC (S (NC (C) (C) C) (=O) =O) =CC=C5
Molecular Formula
C27H35N3O5S2
Molecular Weight
545.71
Storage Conditions
-20°C
Notes
For research use only.
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