Phanginin A
Phanginin A, a natural compound from Caesalpinia sappan, activates SIK1 and inhibits hepatic gluconeogenesis by suppressing the cAMP/PKA/CREB pathway via PDE4 activation. It has demonstrated efficacy in improving metabolic parameters in ob/ob mouse models, making it a useful research tool for studying type 2 diabetes and related metabolic disorders.
Product Specifications
CAS Number
1011528-58-7
Field of Research
Signal Transduction
Purity
95.54% (May vary between batches)
Smiles
O[C@H]1[C@@]23[C@] ([C@@] (C (OC) =O) (CO1) CCC2) (CC[C@@]4 ([C@@]3 (CC5=C ([C@@H]4C) C=CO5) [H]) [H]) [H]
Molecular Formula
C21H28O5
Molecular Weight
360.44
Storage Conditions
-20°C
Notes
For research use only.
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