EGFR-IN-25
EGFR-IN-25 is a potent and selective EGFR inhibitor, exhibiting an IC50 of 9 nM against BaF3 cells harboring the EGFR DEL19/T790M/C797S triple mutation and 60 nM against wild-type EGFR in A431 cells. This small molecule is a valuable research tool for investigating resistance mechanisms in non-small cell lung cancer (NSCLC) and for conducting in vitro efficacy studies.
Product Specifications
CAS Number
2749562-63-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C=1C (=NC (C (N) =O) =C (NC2=CC=C (C=C2) N3CCC (CC3) N4CCN (C) CC4) N1) C5=C6C (NC=C6) =CC=C5) C7CCOCC7
Molecular Formula
C34H43N9O2
Molecular Weight
609.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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