EGFR-IN-30
EGFR-IN-30 is a highly potent small molecule EGFR inhibitor, demonstrating IC50 values in the low nanomolar range against both wild-type and resistant L858R/T790M/C797S mutant forms. It serves as a valuable research tool for investigating EGFR-driven oncogenesis in both cellular and animal models of proliferative diseases like non-small cell lung cancer.
Product Specifications
CAS Number
2726463-68-7
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (C) (C) N1C=2C (C3=C (CC1) N (C) N=C3) =CC (NC=4N=C (NC5=C (P (C) (C) =O) C=CC=C5) C (Br) =CN4) =C (OC) C2
Molecular Formula
C28H33BrN7O2P
Molecular Weight
610.49
Storage Conditions
-20°C
Notes
For research use only.
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