PI3Ka-IN-5
PI3Ka-IN-5 is a potent dual inhibitor of PI3Kα and mTOR, exhibiting IC50 values of 0.7 nM and 3.3 nM, respectively. It is a research compound used in preclinical studies for colorectal cancer, applicable in both in vitro cellular assays and in vivo animal models to investigate oncogenic signaling pathways.
Product Specifications
CAS Number
2237953-19-2
Field of Research
Cancer Biology, Signal Transduction
Smiles
N (C (NC1=CC=C (C (=O) N2[C@H] (C (N) =O) CCC2) C=C1) =O) C3=CC=C (C=4N=C (N=C (N4) N5CCOCC5) N6CCOCC6) C=C3
Molecular Formula
C30H35N9O5
Molecular Weight
601.66
Storage Conditions
-20°C
Notes
For research use only.
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