ThrRS-IN-3
ThrRS-IN-3 is a potent and selective inhibitor of Salmonella enterica threonyl-tRNA synthetase (ThrRS), with an IC50 of 19 nM and a Kd of 34 nM. This compound serves as a valuable chemical tool for studying bacterial protein synthesis and has demonstrated antibacterial activity in both in vitro and in vivo research models.
Product Specifications
Field of Research
Infectious Disease & Virology
Smiles
C[C@H] ([C@@H] (C (=O) N[C@@H] (CNC (=O) CCN1C=NC2=CC (=C (C=C2C1=O) Cl) Cl) C3=CC=CC (=C3) C4=CC5=C (C=C4) C (=O) NC5) N) O
Molecular Formula
C31H30Cl2N6O5
Molecular Weight
637.51
Storage Conditions
-20°C
Notes
For research use only.
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