EGFR-IN-61
EGFR-IN-61 is a potent and selective EGFR kinase inhibitor, showing nanomolar IC50 values against mutant forms including L858R/T790M and L858R/T790M/C797S. It demonstrates antiproliferative activity in cellular assays using A549 and H1975 cancer cell lines, making it a useful research tool for studying EGFR-driven oncogenesis and resistance mechanisms.
Product Specifications
CAS Number
2890261-81-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CN (C) CCN (C) C1=CC (=C (C=C1NC (=O) C2=CC (=NC=C2) Cl) NC3=NC=CC (=N3) C4=CN (C5=CC=CC=C54) CCCO) OC
Molecular Formula
C33H37ClN8O3
Molecular Weight
629.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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