EZH2-IN-14
EZH2-IN-14 is a potent and highly selective small molecule inhibitor of the EZH2 methyltransferase, with an IC50 of 12 nM and >200-fold selectivity over EZH1. It effectively reduces cellular H3K27me3 levels and is a valuable chemical probe for studying PRC2 function in oncology and epigenetics research, both in vitro and in vivo.
Product Specifications
CAS Number
1979157-17-9
Field of Research
Epigenetics & Chromatin
Purity
99.82% (May vary between batches)
Smiles
O=C (NCC=1C (=O) NC (=CC1C) C) C2=CC (=CC3=C2C=NN3C (C) C) C=4C=NC (=CC4) N5CCN (CC5) C (C) C
Molecular Formula
C31H39N7O2
Molecular Weight
541.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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