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EZH2-IN-14

EZH2-IN-14 is a potent and highly selective small molecule inhibitor of the EZH2 methyltransferase, with an IC50 of 12 nM and >200-fold selectivity over EZH1. It effectively reduces cellular H3K27me3 levels and is a valuable chemical probe for studying PRC2 function in oncology and epigenetics research, both in vitro and in vivo.

Product Specifications

CAS Number

1979157-17-9

Field of Research

Epigenetics & Chromatin

Purity

99.82% (May vary between batches)

Smiles

O=C (NCC=1C (=O) NC (=CC1C) C) C2=CC (=CC3=C2C=NN3C (C) C) C=4C=NC (=CC4) N5CCN (CC5) C (C) C

Molecular Formula

C31H39N7O2

Molecular Weight

541.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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