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PHGDH-IN-3

PHGDH-IN-3 is an orally bioavailable small molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 2.8 μM. It is a research tool for investigating PHGDH's role in cancer metabolism and has been utilized in both in vitro and in vivo preclinical studies.

Product Specifications

CAS Number

2893778-31-7

Product Name Alternative

PHGDH

Field of Research

Metabolism Research

Purity

97.24% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:5 mg/mL (10.09 mM) ; DMSO:90 mg/mL (181.62 mM)

Smiles

N (C (=O) C1=CC=C (S (NC2=CC (C (C) =O) =CC=C2) (=O) =O) C=C1) C3=NC (=CS3) C4=CC (F) =CC=C4

Molecular Formula

C24H18FN3O4S2

Molecular Weight

495.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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