PHGDH-IN-3
PHGDH-IN-3 is an orally bioavailable small molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 2.8 μM. It is a research tool for investigating PHGDH's role in cancer metabolism and has been utilized in both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
2893778-31-7
Product Name Alternative
PHGDH
Field of Research
Metabolism Research
Purity
97.24% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:5 mg/mL (10.09 mM) ; DMSO:90 mg/mL (181.62 mM)
Smiles
N (C (=O) C1=CC=C (S (NC2=CC (C (C) =O) =CC=C2) (=O) =O) C=C1) C3=NC (=CS3) C4=CC (F) =CC=C4
Molecular Formula
C24H18FN3O4S2
Molecular Weight
495.55
Storage Conditions
-20°C
Notes
For research use only.
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