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ACT-777991

ACT-777991 is a selective, orally bioavailable CXCR3 antagonist that demonstrates metabolic stability in preclinical models. It potently blocks CXCL11-mediated T cell migration, making it a valuable research tool for investigating inflammatory and autoimmune diseases in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

1967811-46-6

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C (F) (F) (F) C=1SC (=C (N1) C=2C=NC (C (F) (F) F) =NC2) N3C[C@@H] (CCO) N (C (CN4N=C (C) N=C4) =O) CC3

Molecular Formula

C20H20F6N8O2S

Molecular Weight

550.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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