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EGFR-IN-69

EGFR-IN-69 is a potent and selective EGFR inhibitor, showing low nanomolar IC50 values against resistant mutants including L858R/T790M/C797S. It is a valuable research tool for studying non-small-cell lung cancer (NSCLC), applicable in both in vitro enzymatic assays and in vivo xenograft models to investigate resistance mechanisms.

Product Specifications

CAS Number

2433837-65-9

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

ClC=1C (C=2C=3C (N (S (CC) (=O) =O) C2) =CC=CC3) =NC (NC4=C (OC) C=C (C (Cl) =C4) N5CCC (CC5) N6CCN (C) CC6) =NC1

Molecular Formula

C31H37Cl2N7O3S

Molecular Weight

658.64

Storage Conditions

-20°C

Notes

For research use only.

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