EGFR-IN-70
EGFR-IN-70 is a potent and selective EGFR inhibitor, demonstrating anti-proliferative activity in vitro by suppressing EGFR phosphorylation. It shows greater potency against the EGFR L858R/T790M/C797S mutant (IC50 = 23.6 nM) than wild-type EGFR (IC50 = 307.5 nM), making it a useful compound for oncology research, including studies of resistant cancer models.
Product Specifications
Field of Research
Cell Biology
Smiles
CCS (=O) (=O) N1C=C2C3=C1C=C (C=C3) OCCCCCCOC4=C (C=C (C (=C4) NC5=NC=C (C2=N5) Cl) C) N6CCOCC6
Molecular Formula
C31H36ClN5O5S
Molecular Weight
626.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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