CDK7-IN-20
CDK7-IN-20 is a highly selective and irreversible CDK7 inhibitor with a 4 nM IC50, demonstrating >206-fold selectivity over other CDKs. It serves as a valuable chemical probe for investigating CDK7's role in transcription and cell cycle progression, with research applications in areas such as autosomal dominant polycystic kidney disease (ADPKD) models.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C=CC (=O) NC1=CC=C (C=C1) C (=O) NC2=NNC3=C2C=C (C=C3) C4=CC (=CN=C4) NC[C@H] (C5=CC=CC=C5) O
Molecular Formula
C30H26N6O3
Molecular Weight
518.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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