EGFR-IN-73
EGFR-IN-73 (Compound 3f) is a potent and selective inhibitor of the oncogenic EGFR Del19 mutation, demonstrating an IC50 of 119 nM. This small molecule is a valuable chemical probe for in vitro biochemical and cellular research targeting non-small cell lung cancer (NSCLC) driven by this prevalent EGFR alteration.
Product Specifications
CAS Number
2857033-34-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
COC1=C2C=C3C (=C1) N=CN=C3NC4=CC (=C (C=C4OCCOCCO2) F) Cl
Molecular Formula
C19H17ClFN3O4
Molecular Weight
405.81
Storage Conditions
-20°C
Notes
For research use only.
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