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EGFR-IN-73

EGFR-IN-73 (Compound 3f) is a potent and selective inhibitor of the oncogenic EGFR Del19 mutation, demonstrating an IC50 of 119 nM. This small molecule is a valuable chemical probe for in vitro biochemical and cellular research targeting non-small cell lung cancer (NSCLC) driven by this prevalent EGFR alteration.

Product Specifications

CAS Number

2857033-34-0

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

COC1=C2C=C3C (=C1) N=CN=C3NC4=CC (=C (C=C4OCCOCCO2) F) Cl

Molecular Formula

C19H17ClFN3O4

Molecular Weight

405.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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