EGFR-IN-74
EGFR-IN-74 is a potent small molecule inhibitor selectively targeting EGFR L858R/T790M mutations with an IC50 of 138 nM. It induces apoptosis in cancer cells and is a valuable tool for in vitro and in vivo studies of resistant non-small cell lung cancer.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CCOC (=O) C1=C (C2=C (C=CC (=C2) Br) N=C1N3C=CN=C3) N4CCN (CC4) C5=CC=CC=C5NS (=O) (=O) C6=CC=C (C=C6) C (F) (F) F
Molecular Formula
C32H28BrF3N6O4S
Molecular Weight
729.57
Storage Conditions
-20°C
Notes
For research use only.
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