LRRK2-IN-7
LRRK2-IN-7 is a potent and selective LRRK2 kinase inhibitor with an IC50 of 0.9 nM, demonstrating excellent CNS permeability. It is a valuable research tool for investigating LRRK2's role in Parkinson's disease pathogenesis, suitable for both in vitro biochemical assays and in vivo preclinical models.
Product Specifications
CAS Number
2307277-93-4
Product Name Alternative
LRRK2
Field of Research
Cell Biology
Purity
99.26% (May vary between batches)
Solubility
DMSO:80 mg/mL (193 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.96 mM)
Smiles
C (#N) [C@@]1 (C2 (C1) CC2) C=3C=C4N (N=CC4=CC3) C=5C=C (N=CN5) N6C[C@H] (C (C) (C) O) CC6
Molecular Formula
C24H26N6O
Molecular Weight
414.5
Storage Conditions
-20°C
Notes
For research use only.
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