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HCAII-IN-9

HCAII-IN-9 is a potent small molecule inhibitor of human carbonic anhydrase isoforms II, IX, and XII, with respective IC50 values of 1.18 μM, 0.17 μM, and 2.99 μM. It is not permeable to the blood-brain barrier, making it a useful research tool for studying the roles of these enzymes in peripheral physiological and pathological processes, such as tumorigenesis and acid-base regulation, in vitro.

Product Specifications

CAS Number

2878477-18-8

Product Name Alternative

CA XII, Carbonic anhydrase IX, CarbonicAnhydrase, Carbonic anhydrase II, Carbonic Anhydrase

Field of Research

Metabolism Research

Purity

98.63% (May vary between batches)

Solubility

DMSO:55 mg/mL (131.61 mM)

Smiles

S (N) (=O) (=O) C1=C (NC (=O) C2=CC (C) =CC (C) =C2) C=C (Cl) C (S (N) (=O) =O) =C1

Molecular Formula

C15H16ClN3O5S2

Molecular Weight

417.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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