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Notum-IN-1

Notum-IN-1 is an orally bioavailable, brain-penetrant small molecule that selectively inhibits the enzyme Notum, a key negative regulator of Wnt signaling. Its application in research includes both in vitro mechanistic studies and in vivo models for investigating Wnt/β-catenin pathway restoration in neurological and bone-related disorders.

Product Specifications

CAS Number

338419-11-7

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Smiles

OCC1=CN (N=N1) C1=CC (Cl) =C (Cl) C=C1

Molecular Formula

C9H7Cl2N3O

Molecular Weight

244.08

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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