CIAP1 Ligand-Linker Conjugates 7

CIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs[1].

Product Specifications

Product Name Alternative

E3 ligase Ligand-Linker Conjugates 44

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-44.html

Solubility

10 mM in DMSO

Smiles

NCCOCCOCCOCCNC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H]3N(CCC3)C([C@@H](NC([C@@H](N(C(OCC4C5=C(C=CC=C5)C6=C4C=CC=C6)=O)C)C)=O)C7CCCCC7)=O)=O)=O

Molecular Formula

C55H70N6O9

Molecular Weight

959.18

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.