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AMPK-IN-1

AMPK-IN-1 is a small molecule activator of the AMP-activated protein kinase (AMPK), selectively activating the α2β2γ1 isoform with an EC50 of 551 nM. It promotes eEF2 phosphorylation via an mTORC1-independent mechanism and is a valuable tool for studying AMPK signaling in metabolic and cellular stress research in vitro.

Product Specifications

CAS Number

1219739-95-3

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

O (C=1NC=2C (N1) =CC (Cl) =C (C2) C=3C=C4C (=CC3) C=CN4C) C5=CC (C (O) =O) =C (C) C=C5

Molecular Formula

C24H18ClN3O3

Molecular Weight

431.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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