USP7-797
USP7-797 is a potent, selective, and orally active non-covalent USP7 inhibitor with an IC50 of 0.44 nM. It disrupts the USP7-ubiquitin interaction, demonstrating anti-tumor efficacy in vitro and in vivo by inducing apoptosis and suppressing growth in both wild-type and mutant p53 cancer cell lines.
Product Specifications
CAS Number
2413944-70-2
Product Name Alternative
USP7-IN-7, USP7797, USP 7-797
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purity
95.90% (May vary between batches)
Solubility
DMSO:60 mg/mL (117.64 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.47 mM)
Smiles
CC1 (C) C2C1C (=O) N (CC=3SC=4C (C3) =NC=CC4C5=C (C[C@@H]6CNCCO6) C (C) =CC (Cl) =C5) C2=O
Molecular Formula
C27H28ClN3O3S
Molecular Weight
510.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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