RET-IN-13
RET-IN-13 is a potent quinoline-derived RET kinase inhibitor, with IC50 values of 0.5 nM for wild-type RET and 0.9 nM for the V804M mutant. It is a valuable research tool for investigating RET-driven pathologies, including cancers and gastrointestinal disorders, in both cellular and animal models.
Product Specifications
CAS Number
2684258-54-4
Field of Research
Cell Biology, Signal Transduction
Smiles
O (C) C1=CC2=C (C=C1OC) N=CC (=C2) C3=CC=C (CC (NC4=CC (C (F) (F) F) =C (CN5CCN (CC) CC5) C=C4F) =O) C=N3
Molecular Formula
C32H33F4N5O3
Molecular Weight
611.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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ENTH, ID (Clathrin Interactor 1, Epsin-4, Epsin-related Protein, EpsinR, Enthoprotin, Clathrin-interacting Protein Localized in the Trans-Golgi region, Clint, KIAA0171, EPNR, EPN4, CLINT1) (Biotin) discontinued
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