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RET-IN-13

RET-IN-13 is a potent quinoline-derived RET kinase inhibitor, with IC50 values of 0.5 nM for wild-type RET and 0.9 nM for the V804M mutant. It is a valuable research tool for investigating RET-driven pathologies, including cancers and gastrointestinal disorders, in both cellular and animal models.

Product Specifications

CAS Number

2684258-54-4

Field of Research

Cell Biology, Signal Transduction

Smiles

O (C) C1=CC2=C (C=C1OC) N=CC (=C2) C3=CC=C (CC (NC4=CC (C (F) (F) F) =C (CN5CCN (CC) CC5) C=C4F) =O) C=N3

Molecular Formula

C32H33F4N5O3

Molecular Weight

611.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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