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RET-IN-16

RET-IN-16 is a highly potent and selective RET inhibitor, demonstrating low nanomolar IC50 values against wild-type RET and various oncogenic mutants and fusions. Its anticancer properties support its use in preclinical research for investigating RET-driven cancers in both cellular and animal models.

Product Specifications

CAS Number

2259657-48-0

Field of Research

Cell Biology, Signal Transduction

Smiles

O (C1=C2C (=NC (=N1) C=3C=CC=NC3) NN=C2) C4=CC (C (NC5=CC (C (F) (F) F) =C (CN6CCN (C) CC6) C=C5) =O) =CC=C4C

Molecular Formula

C31H29F3N8O2

Molecular Weight

602.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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