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BTK-IN-23

BTK-IN-23 is a potent and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK; IC50 = 12.8 nM) with superior kinase selectivity compared to Ibrutinib. It also potently inhibits the related kinases BLX and BMX. This compound is a valuable research tool for investigating B-cell receptor signaling and related oncology pathways in both cellular and animal models.

Product Specifications

CAS Number

2573048-11-8

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

NC1=C2C (=NN (C2=NC=N1) [C@H]3CN (C (C=C) =O) CCC3) C4=C (C) C=C (OC5=CC=CC=C5) C=C4C

Molecular Formula

C27H28N6O2

Molecular Weight

468.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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